A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il...
A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1β as relevant therapy for gout patients
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Language
English
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Contents
: The role of Monosodium Urate (MSU) crystals in gout pathophysiology is well described, as is the major impact of IL-1β in the inflammatory reaction that constitutes the hallmark of the disease. However, despite the discovery of the NLRP3 inflammasome and its role as a Pattern Recognition Receptor linking the detection of a danger signal (MSU) to...
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Full title
A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1β as relevant therapy for gout patients
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7019178
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7019178
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ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.40650
