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Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fash...

Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fash...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7021802

Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion

About this item

Full title

Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion

Publisher

China: Springer Nature B.V

Journal title

Bone research, 2020-02, Vol.8 (1), p.9-9

Language

English

Formats

Publication information

Publisher

China: Springer Nature B.V

More information

Scope and Contents

Contents

Osteocytes are mechanosensitive bone cells, but little is known about their effects on tumor cells in response to mechanical stimulation. We treated breast cancer cells with osteocyte-derived conditioned medium (CM) and fluid flow-treated conditioned medium (FFCM) with 0.25 Pa and 1 Pa shear stress. Notably, CM and FFCM at 0.25 Pa induced the mesen...

Alternative Titles

Full title

Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7021802

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7021802

Other Identifiers

ISSN

2095-4700

E-ISSN

2095-6231

DOI

10.1038/s41413-020-0083-6

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