Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fash...
Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion
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China: Springer Nature B.V
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Language
English
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China: Springer Nature B.V
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Osteocytes are mechanosensitive bone cells, but little is known about their effects on tumor cells in response to mechanical stimulation. We treated breast cancer cells with osteocyte-derived conditioned medium (CM) and fluid flow-treated conditioned medium (FFCM) with 0.25 Pa and 1 Pa shear stress. Notably, CM and FFCM at 0.25 Pa induced the mesen...
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Full title
Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7021802
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7021802
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ISSN
2095-4700
E-ISSN
2095-6231
DOI
10.1038/s41413-020-0083-6