A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The highly homologous human leukocyte antigen (HLA)-DQ2 molecules, HLA-DQ2.5 and HLA-DQ2.2, are implicated in the pathogenesis of celiac disease (CeD) by presenting gluten peptides to CD4⁺ T cells. However, while HLA-DQ2.5 is strongly associated with disease, HLA-DQ2.2 is not, and the molecular basis underpinning this differential disease associati...
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Full title
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7022145
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7022145
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1914308117
