Interferon target-gene expression and epigenomic signatures in health and disease
Interferon target-gene expression and epigenomic signatures in health and disease
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Multiple type I interferons and interferon-γ (IFN-γ) are expressed under physiological conditions and are increased by stress and infections, and in autoinflammatory and autoimmune diseases. Interferons activate the Jak–STAT signaling pathway and induce overlapping patterns of expression, called ‘interferon signatures’, of canonical interferon-stim...
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Full title
Interferon target-gene expression and epigenomic signatures in health and disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7024546
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7024546
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-019-0466-2