Correlation of age-of-onset of Atopic Dermatitis with Filaggrin loss-of-function variant status
Correlation of age-of-onset of Atopic Dermatitis with Filaggrin loss-of-function variant status
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The genetic background of Atopic Dermatitis (AD) with chronic pruritus is complex.
Filaggrin
(
FLG
) is an essential gene in the epidermal barrier formation s. Loss-of-function (LOF) variants in
FLG
associated with skin barrier dysfunction constitute the most well-known genetic risk factor for AD. In this study, we focused on the...
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Full title
Correlation of age-of-onset of Atopic Dermatitis with Filaggrin loss-of-function variant status
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7026049
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7026049
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-59627-7
