5-Nitrouracil stabilizes the plasma concentration values of 5-FU in colorectal cancer patients recei...
5-Nitrouracil stabilizes the plasma concentration values of 5-FU in colorectal cancer patients receiving capecitabine
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Capecitabine is selectively converted from 5′-DFUR to 5-fluorouracil (5-FU) in tumours by thymidine phosphorylase (TP). We investigated the addition of 5-nitrouracil (5-NU), a TP inhibitor, into blood samples for precise measurements of plasma 5-FU concentrations. The plasma concentration of 5-FU was measured after capecitabine administration. Two...
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5-Nitrouracil stabilizes the plasma concentration values of 5-FU in colorectal cancer patients receiving capecitabine
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7026090
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7026090
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-59648-2
