Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress...
Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Autophagy, a conserved cellular degradation and recycling process, can be enhanced by nutrient depletion, oxidative stress or other harmful conditions to maintain cell survival. 6-Hydroxydopamine/ascorbic acid (6-OHDA/AA) is commonly used to induce experimental Parkinson’s disease (PD) lesions by causing oxidative damage to dopaminergic neurons. Ac...
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Full title
Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7028954
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7028954
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-2322-6
