Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression
Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Retinoblastoma is an aggressive childhood cancer of the developing retina that initiates by biallelic
RB1
gene inactivation. Tumor progression in retinoblastoma is driven by epigenetics, as retinoblastoma genomes are stable, but the mechanism(s) that drive these epigenetic changes remain unknown. Lymphoid-specific helicase (HELLS) protein is...
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Full title
Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7028996
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7028996
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ISSN
2157-9024
E-ISSN
2157-9024
DOI
10.1038/s41389-020-0210-7
