Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect aga...
Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Psoriasis is a common autoimmune and chronic inflammatory skin disorder globally affecting 0.51–11.43% of adults. Inflammation-associated cell death in keratinocytes plays a key role in the process of integrate inflammatory cascade in psoriasis. Necroptosis is a regulated necrotic cell death mediated by receptor interacting protein kinase 1 (RIPK1)...
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Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7031250
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7031250
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ISSN
2041-4889
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2041-4889
DOI
10.1038/s41419-020-2328-0