Positive allosteric modulation of indoleamine 2,3- dioxygenase 1 restrains neuroinflammation
Positive allosteric modulation of indoleamine 2,3- dioxygenase 1 restrains neuroinflammation
About this item
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Author / Creator
Mondanelli, Giada , Coletti, Alice , Greco, Francesco Antonio , Pallotta, Maria Teresa , Orabona, Ciriana , Iacono, Alberta , Belladonna, Maria Laura , Albini, Elisa , Panfili, Eleonora , Fallarino, Francesca , Gargaro, Marco , Manni, Giorgia , Matino, Davide , Carvalho, Agostinho , Cunha, Cristina , Maciel, Patricia , Di Filippo, Massimiliano , Gaetani, Lorenzo , Bianchi, Roberta , Vacca, Carmine , Iamandii, Ioana Maria , Proietti, Elisa , Boscia, Francesca , Annunziato, Lucio , Peppelenbosch, Maikel , Puccetti, Paolo , Calabresi, Paolo , Macchiarulo, Antonio , Santambrogio, Laura , Volpi, Claudia and Grohmann, Ursula
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
L-tryptophan (Trp), an essential amino acid for mammals, is the precursor of a wide array of immunomodulatory metabolites produced by the kynurenine and serotonin pathways. The kynurenine pathway is a paramount source of several immunoregulatory metabolites, including L-kynurenine (Kyn), the main product of indoleamine 2,3-dioxygenase 1 (IDO1) that...
Alternative Titles
Full title
Positive allosteric modulation of indoleamine 2,3- dioxygenase 1 restrains neuroinflammation
Authors, Artists and Contributors
Author / Creator
Coletti, Alice
Greco, Francesco Antonio
Pallotta, Maria Teresa
Orabona, Ciriana
Iacono, Alberta
Belladonna, Maria Laura
Albini, Elisa
Panfili, Eleonora
Fallarino, Francesca
Gargaro, Marco
Manni, Giorgia
Matino, Davide
Carvalho, Agostinho
Cunha, Cristina
Maciel, Patricia
Di Filippo, Massimiliano
Gaetani, Lorenzo
Bianchi, Roberta
Vacca, Carmine
Iamandii, Ioana Maria
Proietti, Elisa
Boscia, Francesca
Annunziato, Lucio
Peppelenbosch, Maikel
Puccetti, Paolo
Calabresi, Paolo
Macchiarulo, Antonio
Santambrogio, Laura
Volpi, Claudia
Grohmann, Ursula
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7035626
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7035626
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1918215117
