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Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment...

Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044037

Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia

About this item

Full title

Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia

Publisher

New York: Nature Publishing Group US

Journal title

Mucosal immunology, 2020-03, Vol.13 (2), p.334-343

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Previous pneumococcal experience establishes lung-resident IL-17A-producing CD4
+
memory T
RM
cells that accelerate neutrophil recruitment against heterotypic pneumococci. Herein, we unravel a novel crosstalk between CD4
+
T
RM
cells and lung epithelial cells underlying this protective immunity. Depletion of CD4
+
cell...

Alternative Titles

Full title

Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044037

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044037

Other Identifiers

ISSN

1933-0219

E-ISSN

1935-3456

DOI

10.1038/s41385-019-0229-2

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