A developed serum-free medium and an optimized chemical cocktail for direct conversion of human derm...
A developed serum-free medium and an optimized chemical cocktail for direct conversion of human dermal fibroblasts into brown adipocytes
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Brown adipocytes coordinate systemic energy metabolism associated with the pathogenesis of obesity and related metabolic diseases including type 2 diabetes. We have previously reported chemical compound-induced brown adipocytes (ciBAs) converted from human dermal fibroblasts without using transgenes. In this study, to reveal a precise molecular mec...
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A developed serum-free medium and an optimized chemical cocktail for direct conversion of human dermal fibroblasts into brown adipocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7048747
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7048747
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-60769-x