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Hypoxia induces the dormant state in oocytes through expression of Foxo3

Hypoxia induces the dormant state in oocytes through expression of Foxo3

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7056940

Hypoxia induces the dormant state in oocytes through expression of Foxo3

About this item

Full title

Hypoxia induces the dormant state in oocytes through expression of Foxo3

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (25), p.12321-12326

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

In mammals, most immature oocytes remain dormant in the primordial follicles to ensure the longevity of female reproductive life. A precise understanding of mechanisms underlying the dormancy is important for reproductive biology and medicine. In this study, by comparing mouse oogenesis in vivo and in vitro, the latter of which bypasses the primord...

Alternative Titles

Full title

Hypoxia induces the dormant state in oocytes through expression of Foxo3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7056940

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7056940

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1817223116

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