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Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7059591

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

About this item

Full title

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

Publisher

India: Department of Orthopedics, General Hospital of Tianjin Medical University, Tianjin, China

Journal title

Neural regeneration research, 2020-08, Vol.15 (8), p.1539-1545

Language

English

Formats

Publication information

Publisher

India: Department of Orthopedics, General Hospital of Tianjin Medical University, Tianjin, China

More information

Scope and Contents

Contents

R453%R741%R363; The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxaminedirectly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Ycells exposed to erastin, it was found that these cell types respond...

Alternative Titles

Full title

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7059591

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7059591

Other Identifiers

ISSN

1673-5374

E-ISSN

1876-7958

DOI

10.4103/1673-5374.274344

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