Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice
About this item
Full title
Author / Creator
Walker, Ryan G. , Barrandon, Ornella , Poggioli, Tommaso , Dagdeviren, Sezin , Carroll, Shannon H. , Mills, Melanie J. , Mendello, Kourtney R. , Gomez, Yanet , Loffredo, Francesco S. , Pancoast, James R. , Macias-Trevino, Claudio , Marts, Colin , LeClair, Katherine B. , Noh, Hye-Lim , Kim, Taekyoon , Banks, Alexander S. , Kim, Jason K. , Cohen, David E. , Wagers, Amy J. , Melton, Douglas A. and Lee, Richard T.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Insulin resistance is associated with aging in mice and humans. We have previously shown that administration of recombinant GDF11 (rGDF11) to aged mice alters aging phenotypes in the brain, skeletal muscle, and heart. While the closely related protein GDF8 has a role in metabolism, limited data are available on the potential metabolic effects of GD...
Alternative Titles
Full title
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice
Authors, Artists and Contributors
Author / Creator
Barrandon, Ornella
Poggioli, Tommaso
Dagdeviren, Sezin
Carroll, Shannon H.
Mills, Melanie J.
Mendello, Kourtney R.
Gomez, Yanet
Loffredo, Francesco S.
Pancoast, James R.
Macias-Trevino, Claudio
Marts, Colin
LeClair, Katherine B.
Noh, Hye-Lim
Kim, Taekyoon
Banks, Alexander S.
Kim, Jason K.
Cohen, David E.
Wagers, Amy J.
Melton, Douglas A.
Lee, Richard T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7067781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7067781
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-61443-y
