Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate canc...
Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Scope and Contents
Contents
: Androgen receptor splice variant 7 (AR-V7) is a leading cause of the development of castration-resistant prostate cancer (CRPC). However, the regulation and function of AR-V7 at levels of post-translational modifications in prostate cancer therapy remain poorly understood. Here, we conducted a library screen of natural products to identify potent...
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Full title
Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7069092
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7069092
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.41849
