Protection from β-cell apoptosis by inhibition of TGF-β/Smad3 signaling
Protection from β-cell apoptosis by inhibition of TGF-β/Smad3 signaling
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Prevailing insulin resistance and the resultant hyperglycemia elicits a compensatory response from pancreatic islet beta cells (β-cells) that involves increases in β-cell function and β-cell mass. However, the sustained metabolic stress eventually leads to β-cell failure characterized by severe β-cell dysfunction and progressive loss of β-cell mass...
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Full title
Protection from β-cell apoptosis by inhibition of TGF-β/Smad3 signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7070087
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7070087
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-2365-8
