Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Type III IFN lambdas (IFN-λ) have recently been described as important mediators of immune responses at barrier surfaces. However, their role in autoimmune diseases such as systemic lupus erythematosus (SLE), a condition characterized by aberrant type I IFN signaling, has not been determined. Here, we identify a nonredundant role for IFN-λ in immun...
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Full title
Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7071891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7071891
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1916897117
