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Establishment and Characterization of a Brca1 -/- , p53 -/- Mouse Mammary Tumor Cell Line

Establishment and Characterization of a Brca1 -/- , p53 -/- Mouse Mammary Tumor Cell Line

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7072850

Establishment and Characterization of a Brca1 -/- , p53 -/- Mouse Mammary Tumor Cell Line

About this item

Full title

Establishment and Characterization of a Brca1 -/- , p53 -/- Mouse Mammary Tumor Cell Line

Publisher

Switzerland: MDPI

Journal title

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1185

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Breast cancer is the most commonly occurring cancer in women and the second most common cancer overall. By the age of 80, the estimated risk for breast cancer for women with germline BRCA1 or BRCA2 mutations is around 80%. Genetically engineered BRCA1-deficient mouse models offer a unique opportunity to study the pathogenesis and therapy of triple...

Alternative Titles

Full title

Establishment and Characterization of a Brca1 -/- , p53 -/- Mouse Mammary Tumor Cell Line

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7072850

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7072850

Other Identifiers

ISSN

1422-0067

E-ISSN

1422-0067

DOI

10.3390/ijms21041185

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