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Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter

Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7076037

Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter

About this item

Full title

Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-03, Vol.10 (1), p.4842, Article 4842

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mutations in the
Plasmodium falciparum
chloroquine resistance transporter (PfCRT) confer resistance to several antimalarial drugs such as chloroquine (CQ) or piperaquine (PPQ), a partner molecule in current artemisinin-based combination therapies. As a member of the Drug/Metabolite Transporter (DMT) superfamily, the vacuolar transporter PfCRT...

Alternative Titles

Full title

Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7076037

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7076037

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-61181-1

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