Dual regulation of p53 by the ribosome maturation factor SBDS
Dual regulation of p53 by the ribosome maturation factor SBDS
About this item
Full title
Author / Creator
Hao, Qian , Wang, Jieqiong , Chen, Yajie , Wang, Shanshan , Cao, Mingming , Lu, Hua and Zhou, Xiang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The Shwachman-Bodian Diamond syndrome (SBDS)-associated gene,
SBDS
, is involved in rRNA synthesis and ribosome maturation, but the role of SBDS in cancer is largely elusive. In this study, we found that SBDS is often overexpressed or amplified in human cancers, and high level of endogenous SBDS is significantly associated with unfavorable pr...
Alternative Titles
Full title
Dual regulation of p53 by the ribosome maturation factor SBDS
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7083877
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7083877
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-2393-4
