Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
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Author / Creator
Lu, Lu , Liu, Qi , Zhu, Yun , Chan, Kwok-Hung , Qin, Lili , Li, Yuan , Wang, Qian , Chan, Jasper Fuk-Woo , Du, Lanying , Yu, Fei , Ma, Cuiqing , Ye, Sheng , Yuen, Kwok-Yung , Zhang, Rongguang and Jiang, Shibo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A novel human coronavirus, Middle East respiratory syndrome coronavirus (MERS-CoV), has caused outbreaks of a SARS-like illness with high case fatality rate. The reports of its person-to-person transmission through close contacts have raised a global concern about its pandemic potential. Here we characterize the six-helix bundle fusion core structu...
Alternative Titles
Full title
Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7091805
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7091805
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4067