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An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization o...

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7095806

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

About this item

Full title

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2004-08, Vol.10 (8), p.871-875

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Passive serotherapy can confer immediate protection against microbial infection, but methods to rapidly generate human neutralizing monoclonal antibodies are not yet available. We have developed an improved method for Epstein-Barr virus transformation of human B cells. We used this method to analyze the memory repertoire of a patient who recovered...

Alternative Titles

Full title

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7095806

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7095806

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1080

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