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Discriminating self from non-self in nucleic acid sensing

Discriminating self from non-self in nucleic acid sensing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7097691

Discriminating self from non-self in nucleic acid sensing

About this item

Full title

Discriminating self from non-self in nucleic acid sensing

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2016-09, Vol.16 (9), p.566-580

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Immune sensing of foreign nucleic acids among abundant self nucleic acids is a hallmark of virus detection and antiviral defence.
Efficient antiviral defence requires a balanced process of sensing foreign nucleic acids and ignoring self nucleic acids. This balance is accomplished by a multilevel, fail-safe system which combines imm...

Alternative Titles

Full title

Discriminating self from non-self in nucleic acid sensing

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7097691

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7097691

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/nri.2016.78

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