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Fosmidomycin biosynthesis diverges from related phosphonate natural products

Fosmidomycin biosynthesis diverges from related phosphonate natural products

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7098449

Fosmidomycin biosynthesis diverges from related phosphonate natural products

About this item

Full title

Fosmidomycin biosynthesis diverges from related phosphonate natural products

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2019-11, Vol.15 (11), p.1049-1056

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Fosmidomycin and related molecules comprise a family of phosphonate natural products with potent antibacterial, antimalarial and herbicidal activities. To understand the biosynthesis of these compounds, we characterized the fosmidomycin producer,
Streptomyces lavendulae
, using biochemical and genetic approaches. We were unable to elicit prod...

Alternative Titles

Full title

Fosmidomycin biosynthesis diverges from related phosphonate natural products

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7098449

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7098449

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-019-0343-1

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