Structure of the neurotensin receptor 1 in complex with β-arrestin 1
Structure of the neurotensin receptor 1 in complex with β-arrestin 1
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Arrestin proteins bind to active, phosphorylated G-protein-coupled receptors (GPCRs), thereby preventing G-protein coupling, triggering receptor internalization and affecting various downstream signalling pathways
1
,
2
. Although there is a wealth of structural information detailing the interactions between GPCRs and G proteins, less i...
Alternative Titles
Full title
Structure of the neurotensin receptor 1 in complex with β-arrestin 1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7100716
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7100716
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-1953-1
