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CD29 identifies IFN-γ–producing human CD8⁺ T cells with an increased cytotoxic potential

CD29 identifies IFN-γ–producing human CD8⁺ T cells with an increased cytotoxic potential

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7104308

CD29 identifies IFN-γ–producing human CD8⁺ T cells with an increased cytotoxic potential

About this item

Full title

CD29 identifies IFN-γ–producing human CD8⁺ T cells with an increased cytotoxic potential

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (12), p.6686-6696

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cytotoxic CD8⁺ T cells can effectively kill target cells by producing cytokines, chemokines, and granzymes. Expression of these effector molecules is however highly divergent, and tools that identify and preselect CD8⁺ T cells with a cytotoxic expression profile are lacking. Human CD8⁺ T cells can be divided into IFN-γ– and IL-2–producing cells. Un...

Alternative Titles

Full title

CD29 identifies IFN-γ–producing human CD8⁺ T cells with an increased cytotoxic potential

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7104308

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7104308

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1913940117

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