Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade th...
Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy
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Author / Creator
Wang, Xiaodong , Yang, Xiaohui , Zhang, Chang , Wang, Yang , Cheng, Tianyou , Duan, Liqiang , Tong, Zhou , Tan, Shuguang , Zhang, Hangjie , Saw, Phei Er , Gu, Yinmin , Wang, Jinhua , Zhang, Yibi , Shang, Lina , Liu, Yajuan , Jiang, Siyuan , Yan, Bingxue , Li, Rong , Yang, Yue , Yu, Jie , Chen, Yunzhao , Gao, George Fu , Ye, Qinong and Gao, Shan
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The programmed cell death 1 (PD-1) receptor on the surface of immune cells is an immune checkpoint molecule that mediates the immune escape of tumor cells. Consequently, antibodies targeting PD-1 have shown efficacy in enhancing the antitumor activity of T cells in some types of cancers. However, the potential effects of PD-1 on tumor cells remain...
Alternative Titles
Full title
Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7104341
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7104341
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1921445117
