CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
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Author / Creator
Ross, Nathan T. , Lohmann, Felix , Carbonneau, Seth , Fazal, Aleem , Weihofen, Wilhelm A. , Gleim, Scott , Salcius, Michael , Sigoillot, Frederic , Henault, Martin , Carl, Sarah H. , Rodríguez-Molina, Juan B. , Miller, Howard R. , Brittain, Scott M. , Murphy, Jason , Zambrowski, Mark , Boynton, Geoffrey , Wang, Yuan , Chen, Aye , Molind, Gregory J. , Wilbertz, Johannes H. , Artus-Revel, Caroline G. , Jia, Min , Akinjiyan, Favour A. , Turner, Jonathan , Knehr, Judith , Carbone, Walter , Schuierer, Sven , Reece-Hoyes, John S. , Xie, Kevin , Saran, Chitra , Williams, Eric T. , Roma, Guglielmo , Spencer, Matt , Jenkins, Jeremy , George, Elizabeth L. , Thomas, Jason R. , Michaud, Gregory , Schirle, Markus , Tallarico, John , Passmore, Lori A. , Chao, Jeffrey A. and Beckwith, Rohan E. J.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The post-genomic era has seen many advances inBaryza and G. Rice for helpful our understanding of cancer pathways, yet resistance and tumor heterogeneity necessitate multiple approaches to target even monogenic tumors. Here, we combine phenotypic screening with chemical genetics to identify pre-messenger RNA endonuclease cleavage and polyadenylatio...
Alternative Titles
Full title
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
Authors, Artists and Contributors
Author / Creator
Lohmann, Felix
Carbonneau, Seth
Fazal, Aleem
Weihofen, Wilhelm A.
Gleim, Scott
Salcius, Michael
Sigoillot, Frederic
Henault, Martin
Carl, Sarah H.
Rodríguez-Molina, Juan B.
Miller, Howard R.
Brittain, Scott M.
Murphy, Jason
Zambrowski, Mark
Boynton, Geoffrey
Wang, Yuan
Chen, Aye
Molind, Gregory J.
Wilbertz, Johannes H.
Artus-Revel, Caroline G.
Jia, Min
Akinjiyan, Favour A.
Turner, Jonathan
Knehr, Judith
Carbone, Walter
Schuierer, Sven
Reece-Hoyes, John S.
Xie, Kevin
Saran, Chitra
Williams, Eric T.
Roma, Guglielmo
Spencer, Matt
Jenkins, Jeremy
George, Elizabeth L.
Thomas, Jason R.
Michaud, Gregory
Schirle, Markus
Tallarico, John
Passmore, Lori A.
Chao, Jeffrey A.
Beckwith, Rohan E. J.
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116157
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-019-0424-1
