Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Acetaldehyde is a highly reactive, DNA-damaging metabolite that is produced upon alcohol consumption
1
. Impaired detoxification of acetaldehyde is common in the Asian population, and is associated with alcohol-related cancers
1
,
2
. Cells are protected against acetaldehyde-induced damage by DNA crosslink repair, which when impai...
Alternative Titles
Full title
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116288
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116288
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2059-5
