Genomic copy number predicts esophageal cancer years before transformation
Genomic copy number predicts esophageal cancer years before transformation
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Recent studies show that aneuploidy and driver gene mutations precede cancer diagnosis by many years
1
–
4
. We assess whether these genomic signals can be used for early detection and pre-emptive cancer treatment using the neoplastic precursor lesion Barrett’s esophagus as an exemplar
5
. Shallow whole-genome sequencing of 777 bi...
Alternative Titles
Full title
Genomic copy number predicts esophageal cancer years before transformation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116403
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116403
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-020-1033-y
