Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-bin...
Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-binding cavities
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Scope and Contents
Contents
Simultaneous binding of molecules by multiple binding partners is known to strongly reduce the apparent dissociation constant of the corresponding molecular complexes, and can be used to achieve strong, non-covalent molecular interactions. Based on this principle, efficient binding of proteins to DNA nanostructures has been achieved previously by p...
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Full title
Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-binding cavities
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116572
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116572
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-020-0504-6
