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STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

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STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116782

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

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Publisher

London: Nature Publishing Group UK

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Contents

Metastatic melanoma is hallmarked by its ability of phenotype switching to more slowly proliferating, but highly invasive cells. Here, we tested the impact of signal transducer and activator of transcription 3 (STAT3) on melanoma progression in association with melanocyte inducing transcription factor (MITF) expression levels. We established a mous...

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Full title

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116782

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116782

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ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-020-01584-6

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