RORα is a critical checkpoint for T cell and ILC2 commitment in the embryonic thymus
RORα is a critical checkpoint for T cell and ILC2 commitment in the embryonic thymus
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Type 2 innate lymphoid cells (ILC2) contribute to immune homeostasis, protective immunity and tissue repair. Here we demonstrate that functional ILC2 cells can arise in the embryonic thymus from shared T cell precursors, preceding the emergence of CD4
+
CD8
+
(double-positive) T cells. Thymic ILC2 cells migrated to mucosal tissues, with...
Alternative Titles
Full title
RORα is a critical checkpoint for T cell and ILC2 commitment in the embryonic thymus
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116838
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116838
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-020-00833-w
