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Toward targeting inflammasomes: insights into their regulation and activation

Toward targeting inflammasomes: insights into their regulation and activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7118104

Toward targeting inflammasomes: insights into their regulation and activation

About this item

Full title

Toward targeting inflammasomes: insights into their regulation and activation

Publisher

Singapore: Springer Singapore

Journal title

Cell research, 2020-04, Vol.30 (4), p.315-327

Language

English

Formats

Publication information

Publisher

Singapore: Springer Singapore

More information

Scope and Contents

Contents

Inflammasomes are multi-component signaling complexes critical to the initiation of pyroptotic cell death in response to invading pathogens and cellular damage. A number of innate immune receptors have been reported to serve as inflammasome sensors. Activation of these sensors leads to the proteolytic activation of caspase-1, a proinflammatory casp...

Alternative Titles

Full title

Toward targeting inflammasomes: insights into their regulation and activation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7118104

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7118104

Other Identifiers

ISSN

1001-0602

E-ISSN

1748-7838

DOI

10.1038/s41422-020-0295-8

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