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Tumor-penetrating peptide for systemic targeting of Tenascin-C

Tumor-penetrating peptide for systemic targeting of Tenascin-C

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7118115

Tumor-penetrating peptide for systemic targeting of Tenascin-C

About this item

Full title

Tumor-penetrating peptide for systemic targeting of Tenascin-C

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-04, Vol.10 (1), p.5809, Article 5809

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Extracellular matrix in solid tumors has emerged as a specific, stable, and abundant target for affinity-guided delivery of anticancer drugs. Here we describe the homing peptide that interacts with the C-isoform of Tenascin-C (TNC-C) upregulated in malignant tissues. TNC-C binding PL3 peptide (amino acid sequence: AGRGRLVR) was identified by
in...

Alternative Titles

Full title

Tumor-penetrating peptide for systemic targeting of Tenascin-C

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7118115

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7118115

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-62760-y

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