Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity
Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Gentamicin is a nephrotoxic antibiotic that causes acute kidney injury (AKI) primarily by targeting the proximal tubule epithelial cell. The development of an effective therapy for gentamicin-induced renal cell injury is limited by incomplete mechanistic insight. To address this challenge, we propose that RNAi signal pathway screening could identif...
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Full title
Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7125232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7125232
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-2382-7
