Selective imaging of solid tumours via the calcium-dependent high-affinity binding of a cyclic octap...
Selective imaging of solid tumours via the calcium-dependent high-affinity binding of a cyclic octapeptide to phosphorylated Annexin A2
About this item
Full title
Author / Creator
Shen, Duanwen , Xu, Baogang , Liang, Kexian , Tang, Rui , Sudlow, Gail P. , Egbulefu, Christopher , Guo, Kevin , Som, Avik , Gilson, Rebecca , Maji, Dolonchampa , Mondal, Suman , Habimana-Griffin, LeMoyne , Akers, Walter J. , Li, Shunqiang , Liu, Yang , Bloch, Sharon , Kurkure, Sid , Nussinov, Zohar , Seidel, Alexander , Tsen, Shaw-Wei D. and Achilefu, Samuel
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The heterogeneity and continuous genetic adaptation of tumours complicate their detection and treatment via the targeting of genetic mutations. However, hallmarks of cancer such as aberrant protein phosphorylation and calcium-mediated cell signalling provide broadly conserved molecular targets. Here, we show that, for a range of solid tumours, a cy...
Alternative Titles
Full title
Selective imaging of solid tumours via the calcium-dependent high-affinity binding of a cyclic octapeptide to phosphorylated Annexin A2
Authors, Artists and Contributors
Author / Creator
Xu, Baogang
Liang, Kexian
Tang, Rui
Sudlow, Gail P.
Egbulefu, Christopher
Guo, Kevin
Som, Avik
Gilson, Rebecca
Maji, Dolonchampa
Mondal, Suman
Habimana-Griffin, LeMoyne
Akers, Walter J.
Li, Shunqiang
Liu, Yang
Bloch, Sharon
Kurkure, Sid
Nussinov, Zohar
Seidel, Alexander
Tsen, Shaw-Wei D.
Achilefu, Samuel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7135742
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7135742
Other Identifiers
ISSN
2157-846X
E-ISSN
2157-846X
DOI
10.1038/s41551-020-0528-7
