Claudin-12 Knockout Mice Demonstrate Reduced Proximal Tubule Calcium Permeability
Claudin-12 Knockout Mice Demonstrate Reduced Proximal Tubule Calcium Permeability
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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The renal proximal tubule (PT) is responsible for the reabsorption of approximately 65% of filtered calcium, primarily via a paracellular pathway. However, which protein(s) contribute this paracellular calcium pore is not known. The claudin family of tight junction proteins confers permeability properties to an epithelium. Claudin-12 is expressed i...
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Full title
Claudin-12 Knockout Mice Demonstrate Reduced Proximal Tubule Calcium Permeability
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7139911
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7139911
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms21062074
