PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
About this item
Full title
Author / Creator
Wang, Tong , Jing, Bo , Xu, Dongliang , Liao, Yueling , Song, Hongyong , Sun, Beibei , Guo, Wenzheng , Xu, Jianhua , Li, Kaimi , Hu, Min , Liu, Shuli , Ling, Jing , Kuang, Yanbin , Zhang, Tuo , Zhang, Siwei , Yao, Feng , Zhou, Binhua P. and Deng, Jiong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chronic inflammation has been linked to promotion of tumorigenesis and metastasis in lung. However, due to lack of a relevant animal model for characterization, the underlying mechanism remains elusive. Lung tumor suppressor gene
Gprc5a
-knockout (ko) mice are susceptible to lung inflammation, tumorigenesis and metastasis, which resembles the...
Alternative Titles
Full title
PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7142021
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7142021
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-1207-6
