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Specific subfamilies of transposable elements contribute to different domains of T lymphocyte enhanc...

Specific subfamilies of transposable elements contribute to different domains of T lymphocyte enhanc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148579

Specific subfamilies of transposable elements contribute to different domains of T lymphocyte enhancers

About this item

Full title

Specific subfamilies of transposable elements contribute to different domains of T lymphocyte enhancers

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (14), p.7905-7916

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Transposable elements (TEs) compose nearly half of mammalian genomes and provide building blocks for cis-regulatory elements. Using high-throughput sequencing, we show that 84 TE subfamilies are overrepresented, and distributed in a lineage-specific fashion in core and boundary domains of CD8⁺ T cell enhancers. Endogenous retroviruses are most sign...

Alternative Titles

Full title

Specific subfamilies of transposable elements contribute to different domains of T lymphocyte enhancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148579

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148579

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1912008117

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