Enhanced myostatin expression and signalling promote tubulointerstitial inflammation in diabetic nep...
Enhanced myostatin expression and signalling promote tubulointerstitial inflammation in diabetic nephropathy
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Myostatin (MSTN), a family member of the transforming growth factor (TGF)-β super family, has been detected in the tubuli of pig kidney, but its role in the human kidney is not known. In this study we observed upregulation of MSTN mRNA (~8 to 10-fold increase) both in the glomeruli and tubulointerstitium in diabetic nephropathy (DN). In DN, immunor...
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Full title
Enhanced myostatin expression and signalling promote tubulointerstitial inflammation in diabetic nephropathy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7156449
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7156449
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-62875-2
