Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesi...
Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions
About this item
Full title
Author / Creator
Ordonez, Alvaro A. , Wang, Hechuan , Magombedze, Gesham , Ruiz-Bedoya, Camilo A. , Srivastava, Shashikant , Chen, Allen , Tucker, Elizabeth W. , Urbanowski, Michael E. , Pieterse, Lisa , Fabian Cardozo, E. , Lodge, Martin A. , Shah, Maunank R. , Holt, Daniel P. , Mathews, William B. , Dannals, Robert F. , Gobburu, Jogarao V. S. , Peloquin, Charles A. , Rowe, Steven P. , Gumbo, Tawanda , Ivaturi, Vijay D. and Jain, Sanjay K.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Tuberculosis (TB) is the leading cause of death from a single infectious agent, requiring at least 6 months of multidrug treatment to achieve cure
1
. However, the lack of reliable data on antimicrobial pharmacokinetics (PK) at infection sites hinders efforts to optimize antimicrobial dosing and shorten TB treatments
2
. In this study,...
Alternative Titles
Full title
Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions
Authors, Artists and Contributors
Author / Creator
Wang, Hechuan
Magombedze, Gesham
Ruiz-Bedoya, Camilo A.
Srivastava, Shashikant
Chen, Allen
Tucker, Elizabeth W.
Urbanowski, Michael E.
Pieterse, Lisa
Fabian Cardozo, E.
Lodge, Martin A.
Shah, Maunank R.
Holt, Daniel P.
Mathews, William B.
Dannals, Robert F.
Gobburu, Jogarao V. S.
Peloquin, Charles A.
Rowe, Steven P.
Gumbo, Tawanda
Ivaturi, Vijay D.
Jain, Sanjay K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7160048
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7160048
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-020-0770-2