Nonclassical nuclear localization signals mediate nuclear import of CIRBP
Nonclassical nuclear localization signals mediate nuclear import of CIRBP
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The specific interaction of importins with nuclear localization signals (NLSs) of cargo proteins not only mediates nuclear import but also, prevents their aberrant phase separation and stress granule recruitment in the cytoplasm. The importin Transportin-1 (TNPO1) plays a key role in the (patho-)physiology of both processes. Here, we report that bo...
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Full title
Nonclassical nuclear localization signals mediate nuclear import of CIRBP
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7165476
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7165476
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1918944117