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Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative...

Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7170916

Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights

About this item

Full title

Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-04, Vol.10 (1), p.6625, Article 6625

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Regulatory authorities require animal toxicity tests for new chemical entities. Organ weight changes are accepted as a sensitive indicator of chemically induced organ damage, but can be difficult to interpret because changes in organ weight might reflect chemically-induced changes in overall body weight. A common solution is to calculate the relati...

Alternative Titles

Full title

Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7170916

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7170916

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-63465-y

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