Serine-dependent redox homeostasis regulates glioblastoma cell survival
Serine-dependent redox homeostasis regulates glioblastoma cell survival
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Background
The amino acid serine is an important substrate for biosynthesis and redox homeostasis. We investigated whether glioblastoma (GBM) cells are dependent on serine for survival under conditions of the tumour microenvironment.
Methods
Serine availability in GBM cells was modulated pharmacologically, genetically and by adjusting seri...
Alternative Titles
Full title
Serine-dependent redox homeostasis regulates glioblastoma cell survival
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7188854
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7188854
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-020-0794-x
