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Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Chitinase 3-like 1 is neurotoxic in primary cultured neurons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7188887

Chitinase 3-like 1 is neurotoxic in primary cultured neurons

About this item

Full title

Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-04, Vol.10 (1), p.7118, Article 7118

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Chitinase 3-like 1 (CHI3L1) is known to play a role as prognostic biomarker in the early stages of multiple sclerosis (MS), and patients with high cerebrospinal fluid CHI3L1 levels have an increased risk for the development of neurological disability. Here, we investigated its potential neurotoxic effect by adding recombinant CHI3L1
in vitro
...

Alternative Titles

Full title

Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7188887

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7188887

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-64093-2

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