Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6
Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lineage selective transcription factors (TFs) are important regulators of tumorigenesis, but their biological functions are often context dependent with undefined epigenetic mechanisms of action. In this study, we uncover a conditional role for the endodermal and pulmonary specifying TF GATA6 in lung adenocarcinoma (LUAD) progression. Impairing
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Full title
Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7190573
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7190573
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-1246-z
