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Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7190993

Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

About this item

Full title

Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2020-05, Vol.130 (5), p.2673-2688

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Tumor-associated peptide-human leukocyte antigen complexes (pHLAs) represent the largest pool of cell surface-expressed cancer-specific epitopes, making them attractive targets for cancer therapies. Soluble bispecific molecules that incorporate an anti-CD3 effector function are being developed to redirect T cells against these targets using 2 diffe...

Alternative Titles

Full title

Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7190993

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7190993

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI130562

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