Plasmacytoid dendritic cell deficiency in neonates enhances allergic airway inflammation via reduced...
Plasmacytoid dendritic cell deficiency in neonates enhances allergic airway inflammation via reduced production of IFN-α
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Author / Creator
Wu, Min , Gao, Liuchuang , He, Miao , Liu, Hangyu , Jiang, Han , Shi, Ketai , Shang, Runshi , Liu, Bing , Gao, Shan , Chen, Hebin , Gong, Feili , Gelfand, Erwin W. , Huang, Yafei and Han, Junyan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Allergic asthma, a chronic inflammatory airway disease associated with type 2 cytokines, often originates in early life. Immune responses at an early age exhibit a Th2 cell bias, but the precise mechanisms remain elusive. Plasmacytoid dendritic cells (pDCs), which play a regulatory role in allergic asthma, were shown to be deficient in neonatal mic...
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Full title
Plasmacytoid dendritic cell deficiency in neonates enhances allergic airway inflammation via reduced production of IFN-α
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7192848
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7192848
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ISSN
1672-7681
E-ISSN
2042-0226
DOI
10.1038/s41423-019-0333-y
